Targeted issues

Wrinkles, global skin-aging, lack of radiance, dark spots, cutaneous asphyxia.

Cosmeceutical benefits

• Increases your skin’s resilience to oxidative stress from blue light and UV rays
• Protects against oxidative stress caused by urban pollution, shielding your skin against damage from micro-particles
• Activates DNA repair enzymes, reducing the effects of oxidative damage.
• Increases cell energy, by boosting production of mitochondrial production of ATP, which is key to powering cells, and blocking the formation of free radicals
• Stimulates collagen and elastin production while inhibiting the glycation process (reduction in the elasticity of collagen fibres), helping to keep your skin firm and soft. This has been proven in in vivo tests to be effective in reducing the appearance of lines and wrinkles
• Strengthens and maintains your natural skin barrier. It increases hydration, preventing your skin from losing moisture and delaying the early signs of ageing
• IAccelerates tissue repair following damage from stress

Nescens cosmeceutical system

As part of the Nescens cosmeceutical skincare program, use the high-power defence bosster on a perfectly cleansed and dry skin, or in complement with your serum, correcting care or mask to boost their effects.

Main active ingredients

«Superfood» for skin Niacinamide: - Significantly reduces the presence of ROS and the level of oxidized proteins in response to blue light radiation.
- Combats UV damage by protecting and repairing tissues stressed by ultra-violet radiation.
- Increases resistance to oxidative stress in epidermal cells exposed to particulate pollution and limits the formation of dark spots.
- Activates enzymes involved in DNA repair (poly-ADP-ribose-polymerase) and limits the consequences of oxidative damage.
- Increases mitochondrial production of ATP, which is key to powering cells, and restricts the formation of free radicals (partly due to conversion to nicotinamide adenine nucleotide [NAD+]). Re-energizes your skin to help guard against environmental factors.
- Increases fibroblast expression of skin genes involved in the synthesis of mec components, significantly inhibits the process of glycation (hardening of collagen fibres leading to wrinkle formation), and increases proteasome activity (elimination of damaged molecules). Helps keep your skin firm and smooth and reduces the appearance of wrinkles and lines.
- Activates sirtuins involved in the process of molecular maintenance and repair.
- Reinforces the barrier function by increasing the ratio of ceramides and free fatty acids, lipids present in the epidermis.
- Boosts hydration, limits insensible water loss, relieves dryness, desquamation and inflammation.

Special grade of niacinamide: Offers all the advantages of vitamin B3, while minimizing the potential undesirable effects identified, such as warming sensations in the skin caused by residual nicotinic acid. Guaranteed to contain less than 100 ppm of residual nicotinic acid, which means it is exceptionally well tolerated.

Dexpanthenol: - Has an anti-inflammatory effect on erythema caused by UV, helping the skin to preserve its elasticity, evenness and radiance.
- Promotes the expression of genes involved in tissue repair.
- Facilitates the proliferation of fibroblasts and boosts collagen and elastine production.
- Participates in the reorganization of intercellular lipids.
- Boosts hydration, limits insensible water loss, relieves dryness, desquamation and inflammation.